CSNK1A1 Antikörper

Produktnummer ABIN437965

Dieser Huhn Polyklonal Antikörper detektiert spezifisch CSNK1A1 in WB, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CSNK1A1 Antikörper (ABIN437965)

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Reaktivität: Human

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser CSNK1A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Produktdetails anti-CSNK1A1 Antikörper

Kreuzreaktivität: Human

Immunogen: Human Casein Kinase 1 alpha protein.

Isotyp: IgY

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: -20 °C

Details zu CSNK1A1

Target: CSNK1A1 (Casein Kinase 1, alpha 1 (CSNK1A1))

Hintergrund: The CKI family consists of several different genes, divided in alpha, beta, gamma, delta and epsilon, some of which are encoded by more than one gene. The single mammalian CK1 alpha gene can generate four different proteins by alterate transcription. CK1a was raised against the shortest of these proteins, and will therefore bind to all CK1 isotypes. The CK1 alpha proteins are involved in the control of protein degradation, and phosphorylate acidic regions of their substrate molecules. Typically the target ser/thr residues closely C-terminal to two or three aspartic or glutamic acid residues. Alternately, phosphorylation on residues 3 or 4 amino acids N-terminal to a ser/thr residue can also favor CKI phosphorylation. This means that CKI family enzymes often phosphorylate one or more ser/thr residues C-terminal to a phosphorylation site generated by the activity of another protein kinase.

Pathways: WNT Signalweg, Hedgehog Signalweg