c-MET Antikörper (AA 1001-1005)
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- Target Alle c-MET (MET) Antikörper anzeigen
- c-MET (MET) (Met Proto-Oncogene (MET))
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Bindungsspezifität
- AA 1001-1005
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser c-MET Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- The antibody detects endogenous levels of total Met protein.
- Aufreinigung
- Affinity Chromatography using epitope-specific immunogen.
- Immunogen
- Peptide sequence around amino acids 1001~1005 (V-D-Y-R-A) derived from Human Met.
- Top Product
- Discover our top product MET Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- PBS (without Mg2+ and Ca2+), pH 7.4, containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % glycerol
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- -20 °C
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- Target
- c-MET (MET) (Met Proto-Oncogene (MET))
- Andere Bezeichnung
- HGF Receptor (MET Produkte)
- Hintergrund
- The c-Met oncogene was originally isolated from chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met
- Gen-ID
- 4233
- NCBI Accession
- NP_000236
- UniProt
- P08581
- Pathways
- RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor
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