c-MET Antikörper (AA 1001-1005)

Produktnummer ABIN401652

Dieses Anti-c-MET-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von c-MET in WB und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für c-MET Antikörper (AA 1001-1005) (ABIN401652)

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser c-MET Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-c-MET Antikörper

Bindungsspezifität: AA 1001-1005

Spezifität: The antibody detects endogenous levels of total Met protein.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Immunogen: Peptide sequence around amino acids 1001~1005 (V-D-Y-R-A) derived from Human Met.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS (without Mg2+ and Ca2+), pH 7.4, containing 150 mM NaCl, 0.02 % Sodium Azide and 50 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Details zu c-MET

Target: c-MET (MET) (Met Proto-Oncogene (MET))

Andere Bezeichnung: HGF Receptor

Hintergrund: The c-Met oncogene was originally isolated from chemical carcinogen-treated human osteogenic sarcoma cell line by transfection analysis in NIH/3T3 cells. The Met proto-oncogene product was identified as a trans-membrane receptor-like protein with tyrosine kinase activity that is expressed in many tissues. The c-Met gene product has been identified as the cell surface receptor for hepatocyte growth factor, a plasminogen-like protein thought to be a humoral mediator of liver regeneration.Synonyms: HGF/SF receptor, Hepatocyte growth factor receptor, MET, Met proto-oncogene tyrosine kinase, Scatter factor receptor, c-Met

Gen-ID: 4233

NCBI Accession: NP_000236

UniProt: P08581

Pathways: RTK Signalweg, Carbohydrate Homeostasis, Synaptic Membrane, Signaling of Hepatocyte Growth Factor Receptor