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Paxillin Antikörper (Tyr88)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Paxillin in WB und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN401644

Kurzübersicht für Paxillin Antikörper (Tyr88) (ABIN401644)

Target

Alle Paxillin (PXN) Antikörper anzeigen
Paxillin (PXN)

Reaktivität

  • 215
  • 109
  • 77
  • 17
  • 8
  • 8
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 209
  • 27
  • 1
Kaninchen

Klonalität

  • 186
  • 51
Polyklonal

Konjugat

  • 128
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Dieser Paxillin Antikörper ist unkonjugiert

Applikation

  • 170
  • 65
  • 48
  • 41
  • 40
  • 26
  • 25
  • 25
  • 24
  • 18
  • 14
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF)
  • Bindungsspezifität

    • 33
    • 32
    • 22
    • 16
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr88

    Spezifität

    Paxillin Antibody detects endogenous levels of total Paxillin protein.

    Aufreinigung

    Affinity chromatography

    Immunogen

    Synthesized non-phosphopeptide derived from human Paxillin around the phosphorylation site of tyrosine 88 (P-V-YP-G-S).
  • Applikationshinweise

    Western Blot: 1/500 - 1/1000. Immunofluorescence: 1/100 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    1,0 mg/mL

    Buffer

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    -20 °C
  • Target

    Paxillin (PXN)

    Andere Bezeichnung

    Paxillin / PXN

    Hintergrund

    Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691

    Gen-ID

    5829

    NCBI Accession

    NP_001074324

    UniProt

    P49023

    Pathways

    MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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