CDK2 Antikörper

Produktnummer ABIN400761

Der Maus Monoklonal anti-CDK2 Antikörper (Klon 4i33) (ABIN400761) detektiert spezifisch CDK2 in WB, IP, IHC (p) und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Xenopus laevis.

Kurzübersicht für CDK2 Antikörper (ABIN400761)

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reaktivität: Human, Maus, Xenopus laevis

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CDK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Klon: 4i33

Produktdetails anti-CDK2 Antikörper

Spezifität: Recognizes Human CDK2 (MW 33 kDa). Does not cross-react with other CDKs.

Kreuzreaktivität (Details): Species reactivity (expected):Xenopus and Mouse.
Species reactivity (tested):Human.

Produktmerkmale: Synonyms: p33 protein kinase, Cell division protein kinase 2, Cyclin dependent kinase 2

Aufreinigung: Protein G Chromatography

Immunogen: Recombinant Human CDK2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA. Western blot. Immunoprecipitation. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.85 mg/mL

Buffer: 0.1 M Tris-glycine, pH 7.4, 150 mM Sodium Chloride, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu CDK2

Target: CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Andere Bezeichnung: CDK2

Hintergrund: Cdk2 is a member of the Ser/Thr protein kinase family. It is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and is essential for cell cycle G1/S phase transition. This protein associates with and is regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported.Synonyms: Cell division protein kinase 2, Cyclin dependent kinase 2, p33 protein kinase

Gen-ID: 1017

UniProt: P24941

Pathways: PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA