SARM1 Antikörper

Produktnummer ABIN400726

Dieser Maus Monoklonal Antikörper detektiert spezifisch SARM1 in IP und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für SARM1 Antikörper (ABIN400726)

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SARM1 Antikörper ist unkonjugiert

Applikation: Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: Sarmy-1

Produktdetails anti-SARM1 Antikörper

Spezifität: This antibody recognizes Sterile Alpha And TIR Motif Containing 1 (SARM1).

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Produktmerkmale: Synonyms: SARM, SAMD2, KIAA0524, Sterile alpha and TIR motif-containing protein 1, SAMdomain-containing protein 2, Sterile alpha and Armadillo repeat protein, Sterile alphamotif domain-containing protein 2

Aufreinigung: Protein G Chromatography.

Immunogen: Synthetic peptide - KLH conjugated.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Immunoprecipitation: 1/200. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 10 % Glycerol and 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C forlonger. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu SARM1

Target: SARM1 (Sterile alpha and TIR Motif Containing 1 (SARM1))

Andere Bezeichnung: SARM1

Hintergrund: Toll-like receptors (TLRs) play an essential role in the detection and elimination of invading microbes. They are type-1 transmembrane receptors, containing extracellular leucine rich repeats and an intracellular Toll/interleukin-1 receptor (TIR) domain. Upon stimulation, these receptors interact with specific TIR domain-containing adaptor proteins. Five such adaptors have been discovered to date, MyD88, Mal (MyD88 adaptor-like)/TIRAP (TIR domain-containing adaptor protein), Trif (TIR-domain-containing adaptor inducing interferon-beta), TRAM (Trif-related adaptor molecule) and SARM (SAM and ARM-containing protein). Different TLRs use different combinations of these adaptors, leading to the activation of common and unique pathways involved in the elimination of the invading microbe.Synonyms: KIAA0524, SAM domain-containing protein 2, SAMD2, SARM, Sterile alpha and Armadillo repeat protein, Sterile alpha and TIR motif-containing protein 1, Sterile alpha motif domain-containing protein 2

Gen-ID: 23098

UniProt: Q6SZW1

Pathways: TLR Signalweg, Activation of Innate immune Response, Toll-Like Receptors Cascades