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CDK2 Antikörper (C-Term)

Dieses Anti-CDK2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CDK2 in WB, FACS und IHC (p). Geeignet für Human. Dieses Primary Antibody wurde in 1 Publikation zitiert.
Produktnummer ABIN391746

Kurzübersicht für CDK2 Antikörper (C-Term) (ABIN391746)

Target

Alle CDK2 Antikörper anzeigen
CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

Reaktivität

  • 214
  • 118
  • 93
  • 13
  • 12
  • 11
  • 8
  • 8
  • 8
  • 7
  • 6
  • 6
  • 6
  • 4
  • 3
  • 3
  • 2
Human

Wirt

  • 211
  • 33
  • 1
Kaninchen

Klonalität

  • 190
  • 55
Polyklonal

Konjugat

  • 127
  • 20
  • 16
  • 9
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser CDK2 Antikörper ist unkonjugiert

Applikation

  • 206
  • 80
  • 77
  • 52
  • 50
  • 46
  • 39
  • 34
  • 30
  • 27
  • 9
  • 8
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB3128
  • Bindungsspezifität

    • 28
    • 28
    • 16
    • 15
    • 13
    • 13
    • 12
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 230-260, C-Term

    Homologie

    B, Ha, M, Rat, X

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This CDK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDK2.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Zang, Zhang, Gao, Huang: "Ophiopogonin D inhibits cell proliferation, causes cell cycle arrest at G2/M, and induces apoptosis in human breast carcinoma MCF-7 cells." in: Journal of integrative medicine, Vol. 14, Issue 1, pp. 51-9, (2016) (PubMed).

  • Target

    CDK2 (Cyclin-Dependent Kinase 2 (CDK2))

    Andere Bezeichnung

    CDK2

    Hintergrund

    CDK2 is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation.

    Molekulargewicht

    33930

    Gen-ID

    1017

    NCBI Accession

    NP_001789, NP_439892

    UniProt

    P24941

    Pathways

    PI3K-Akt Signalweg, Zellzyklus, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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