MAPK11 Antikörper (C-Term)

Produktnummer ABIN391730

Der Kaninchen Polyklonal Anti-MAPK11 Antikörper wurde für WB validiert. Er ist geeignet, MAPK11 in Proben von Human und Maus zu detektieren.

Kurzübersicht für MAPK11 Antikörper (C-Term) (ABIN391730)

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MAPK11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB6825

Produktdetails anti-MAPK11 Antikörper

Bindungsspezifität: AA 334-359, C-Term

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-359 amino acids from the C-terminal region of human MAPK11.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Haltbarkeit: 6 months

Details zu MAPK11

Target: MAPK11 (Mitogen-Activated Protein Kinase 11 (MAPK11))

Andere Bezeichnung: P38beta

Hintergrund: P38 beta is a member of the MAP kinase subfamily of Ser/Thr protein kinases. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is closely related to p38 MAP kinase, both of which can be activated by changes in osmolarity of the extracellular environment, proinflammatory cytokines and cellular stress. This protein preferentially phosphorylates transcription factor ATF2. It is activated by phosphorylation on threonine and tyrosine by MKK6, and inhibited by pyridinyl-imidazole related compounds. Highest levels of expression are found in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.

Molekulargewicht: 41357

NCBI Accession: NP_002742

UniProt: Q15759

Pathways: MAPK Signalweg, Neurotrophin Signalübertragung, Activation of Innate immune Response, Response to Water Deprivation, Regulation of Muscle Cell Differentiation, ER-Nucleus Signaling, Hepatitis C, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteine