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ERK1 Antikörper (N-Term)

Name: ERK1 Antikörper (N-Term)
SKU: ABIN391719
Price: 467.5 EUR
Availability: InStock

MAPK3 Reaktivität: Human, Maus, Ratte, Affe WB, IHC (p), FACS Wirt: Kaninchen Polyclonal RB0980 unconjugated

Western blot analysis of ERK1 (arrow) using rabbit ERK1 (N-term) Pab (ABIN391719 and ABIN2841609). (ERK1 Antikörper (N-Term))

PK3 Antibody (N-term) (ABIN391719 and ABIN2841609) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (ERK1 Antikörper (N-Term))

FACS

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ERK1 Antikörper (N-Term))

IHC (p)

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with ERK1 antibody (N-term) (ABIN391719 and ABIN2841609) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (ERK1 Antikörper (N-Term))

IHC (p)

4 Abbildungen

Produktnummer ABIN391719

Datenblatt (PDF)

Target Alle ERK1 (MAPK3) Antikörper anzeigen

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))
Bindungsspezifität
65

43

20

16

15

15

11

10

10

9

7

6

6

6

5

4

3

3

3

3

3

3

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-30, N-Term
Reaktivität
217

162

134

44

20

19

16

12

10

9

9

7

6

5

5

4

3

3

1

1

1

1

1
Human, Maus, Ratte, Affe
Wirt
221

31

3

1

1
Kaninchen
Passende Sekundärantikörper
Klonalität
202

55
Polyklonal
Konjugat
110

17

16

14

7

7

5

5

5

5

5

5

5

5

5

5

5

3

3

3

3

3

3

2

2

2

2

2

2

1
Dieser ERK1 Antikörper ist unkonjugiert
Applikation
205

78

69

68

65

42

40

35

32

21

18

11

7

5

3

2

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This MAPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MAPK3.

Klon

RB0980

Isotyp

Ig Fraction

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MAPK3 Reaktivität: Ratte WB, IHC, IF, FACS, ICC Wirt: Kaninchen Polyclonal HRP

Applikationshinweise

WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Andere Bezeichnung

ERK1 (MAPK3 Produkte)

Hintergrund

ERK1, a member of the MAP kinase subfamily of Ser/Thr protein kinases, is involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK-1. It phosphorylates EIF4EBP1 and is required for initiation of translation. The protein also phosphorylates microtubule-associated protein-2 (MAP2). ERK1 is activated and tyrosine phosphorylated in response to insulin and NGF.

Molekulargewicht

43136

Gen-ID

5595

NCBI Accession

NP_001035145, NP_001103361, NP_002737

UniProt

P27361

Pathways

MAPK Signalweg, RTK Signalweg, Interferon-gamma Pathway, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteine