Tyrosinase-Related Protein 1 Antikörper (AA 198-227)

Produktnummer ABIN391549

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Tyrosinase-Related Protein 1 in FACS, WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human und wurde in 1 Publikation erwähnt.

Kurzübersicht für Tyrosinase-Related Protein 1 Antikörper (AA 198-227) (ABIN391549)

Target: Tyrosinase-Related Protein 1 (TYRP1)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Tyrosinase-Related Protein 1 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB19412

Produktdetails anti-Tyrosinase-Related Protein 1 Antikörper

Bindungsspezifität: AA 198-227

Homologie: Pr

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CATB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-227 amino acids from the Central region of human CATB.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Tyrosinase-Related Protein 1 Antikörper (ABIN391549)

Jensen, Petterson, Halle, Aaberg-Jessen, Kristensen: "Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo." in: BMC cancer, Vol. 17, Issue 1, pp. 178, (2018) (PubMed).

Details zu Tyrosinase-Related Protein 1

Target: Tyrosinase-Related Protein 1 (TYRP1)

Andere Bezeichnung: CATB

Hintergrund: The protein CATB is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors.

Molekulargewicht: 37822

Gen-ID: 1508

NCBI Accession: NP_001899, NP_680090, NP_680091, NP_680092, NP_680093

UniProt: P07858