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Cyclin A Antikörper (N-Term)

Der Kaninchen Polyklonal Anti-Cyclin A-Antikörper wurde für WB, FACS und IHC (p) validiert. Er ist geeignet, Cyclin A in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.
Produktnummer ABIN391454

Kurzübersicht für Cyclin A Antikörper (N-Term) (ABIN391454)

Target

Alle Cyclin A (CCNA2) Antikörper anzeigen
Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

Reaktivität

  • 87
  • 55
  • 34
  • 29
  • 14
  • 14
  • 12
  • 6
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 59
  • 34
  • 1
Kaninchen

Klonalität

  • 47
  • 47
Polyklonal

Konjugat

  • 68
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser Cyclin A Antikörper ist unkonjugiert

Applikation

  • 59
  • 31
  • 24
  • 21
  • 20
  • 17
  • 14
  • 11
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon

RB14617
  • Bindungsspezifität

    • 11
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 51-84, N-Term

    Aufreinigung

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This Cyclin A (CCNA2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 51-84 amino acids from the N-terminal region of human Cyclin A (CCNA2).

    Isotyp

    Ig Fraction
  • Applikationshinweise

    WB: 1:2000. IHC-P: 1:50~100. FC: 1:10~50

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Haltbarkeit

    6 months
  • Chang, Nam, Kook, Kim, Liu, Yao, Jung, Lemos, Seo, Park, Gim, Hong, Huh, Kim, Tan, Liu, Powis, Park, Liang, Kim: "HNF4? is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer." in: Gut, (2014) (PubMed).

  • Target

    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

    Andere Bezeichnung

    Cyclin A (CCNA2)

    Hintergrund

    CCNA2 belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions.

    Molekulargewicht

    48551

    Gen-ID

    890

    NCBI Accession

    NP_001228

    UniProt

    P20248

    Pathways

    PI3K-Akt Signalweg, Zellzyklus, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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