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MAP3K12 Antikörper (C-Term)

MAP3K12 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB0976 unconjugated
Produktnummer ABIN391319
  • Target Alle MAP3K12 Antikörper anzeigen
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Bindungsspezifität
    • 7
    • 7
    • 5
    • 2
    • 1
    • 1
    • 1
    AA 828-859, C-Term
    Reaktivität
    • 35
    • 19
    • 12
    Human, Maus
    Wirt
    • 34
    • 2
    Kaninchen
    Klonalität
    • 34
    • 2
    Polyklonal
    Konjugat
    • 13
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser MAP3K12 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 23
    • 16
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This ZPK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-859 amino acids from the C-terminal region of human ZPK.
    Klon
    RB0976
    Isotyp
    Ig Fraction
  • Applikationshinweise
    WB: 1:2000. IHC-P: 1:50~100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Ye, Li, Yang, Xie, Yu, Ma, Zhu, Zhao, Lv: "MicroRNA-130a Targets MAP3K12 to Modulate Diabetic Endothelial Progenitor Cell Function." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 36, Issue 2, pp. 712-26, (2015) (PubMed).

    Couture, Blouin: "The DLK gene is a transcriptional target of PPAR?." in: The Biochemical journal, Vol. 438, Issue 1, pp. 93-101, (2011) (PubMed).

  • Target
    MAP3K12 (Mitogen-Activated Protein Kinase Kinase Kinase 12 (MAP3K12))
    Andere Bezeichnung
    ZPK (MAP3K12 Produkte)
    Synonyme
    DLK antikoerper, MEKK12 antikoerper, MUK antikoerper, ZPK antikoerper, ZPKP1 antikoerper, PK antikoerper, Zpk antikoerper, zgc:77370 antikoerper, MGC151798 antikoerper, dlk antikoerper, map3k12 antikoerper, map3k12a antikoerper, mekk12 antikoerper, muk antikoerper, zpk antikoerper, zpkp1 antikoerper, DKFZp459K2433 antikoerper, map3k12-a antikoerper, map3k12-b antikoerper, map3k12b antikoerper, mitogen-activated protein kinase kinase kinase 12 antikoerper, mitogen activated protein kinase kinase kinase 12 antikoerper, mitogen-activated protein kinase kinase kinase 12 S homeolog antikoerper, mitogen-activated protein kinase kinase kinase 12 L homeolog antikoerper, MAP3K12 antikoerper, Map3k12 antikoerper, map3k12 antikoerper, map3k12.S antikoerper, map3k12.L antikoerper
    Hintergrund
    ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
    Molekulargewicht
    93219
    Gen-ID
    7786
    NCBI Accession
    NP_001180440, NP_006292
    UniProt
    Q12852
    Pathways
    MAPK Signalweg
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