PDK3 Antikörper (N-Term)
Kurzübersicht für PDK3 Antikörper (N-Term) (ABIN391038)
Target
Alle PDK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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    - 
                                            Bindungsspezifität
- AA 1-30, N-Term
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                                            Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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                                            Immunogen
- This PDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK3.
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                                            Isotyp
- Ig Fraction
 
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- 
    
- 
    - 
                                            Applikationshinweise
- WB: 1:1000. WB: 1:1000
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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                                            Konservierungsmittel
- Sodium azide
- 
                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- 4 °C,-20 °C
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                                            Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 
                                            Haltbarkeit
- 6 months
 
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- 
    - 
                                            : "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons."    in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010)         (PubMed).        
 : "Pyruvate dehydrogenase complex activity controls metabolic and malignant phenotype in cancer cells." in: The Journal of biological chemistry, Vol. 283, Issue 33, pp. 22700-8, (2008) (PubMed).
 
 
- 
                                            : "Phosphorylation status of pyruvate dehydrogenase distinguishes metabolic phenotypes of cultured rat brain astrocytes and neurons."    in: Glia, Vol. 58, Issue 10, pp. 1168-76, (2010)         (PubMed).        
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    - PDK3 (Pyruvate Dehydrogenase Kinase, Isozyme 3 (PDK3))
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                                            Andere Bezeichnung
- PDK3
- 
                                            Hintergrund
- PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
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                                            Molekulargewicht
- 46939
- 
                                            Gen-ID
- 5165
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                                            NCBI Accession
- NP_001135858, NP_005382
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                                            UniProt
- Q15120
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                                            Pathways
- PI3K-Akt Signalweg, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt
 Target
- 
                    
 
                                     
                                     
                                    