ATF2 Antikörper (pSer322)

Produktnummer ABIN389760

Dieser Anti-ATF2-Antikörper ist ein Kaninchen-Polyklonal-Antikörper zum Nachweis von ATF2 in DB. Geeignet für Human.

Kurzübersicht für ATF2 Antikörper (pSer322) (ABIN389760)

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATF2 Antikörper ist unkonjugiert

Applikation: Dot Blot (DB)

Klon: RB10901

Produktdetails anti-ATF2 Antikörper

Bindungsspezifität: pSer322

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This ATF2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S322 of human ATF2.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: DB: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu ATF2

Target: ATF2 (Activating Transcription Factor 2 (ATF2))

Andere Bezeichnung: ATF2

Hintergrund: ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components.

Molekulargewicht: 54537

Gen-ID: 1386

NCBI Accession: NP_001243019, NP_001243020, NP_001243021, NP_001243022, NP_001243023, NP_001871

UniProt: P15336

Pathways: MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades