PCNA Antikörper (AA 89-117)
Kurzübersicht für PCNA Antikörper (AA 89-117) (ABIN389345)
Target
Alle PCNA Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 89-117
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Homologie
- B, C, Ha, Pr, M, Rat
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Aufreinigung
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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Immunogen
- This PCNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the Central region of human PCNA.
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Isotyp
- Ig Fraction
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Applikationshinweise
- IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 6 months
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- PCNA (Proliferating Cell Nuclear Antigen (PCNA))
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Andere Bezeichnung
- PCNA
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Hintergrund
- PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.
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Molekulargewicht
- 28769
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Gen-ID
- 5111
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NCBI Accession
- NP_002583, NP_872590
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UniProt
- P12004
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Pathways
- Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie
Target
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