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PCNA Antikörper (AA 89-117)

Name: PCNA Antikörper (AA 89-117)
SKU: ABIN389345
Price: 445.5 EUR
Availability: InStock

PCNA Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB17485 unconjugated

Western blot analysis of PCNA Antibody (Center) (ABIN389345 and ABIN2839454) in Jurkat(lane 1), Hela(lane 2), 293(lane 3) cell line lysates (35 μg/lane). (PCNA Antikörper (AA 89-117))

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with PCNA antibody (Center) (ABIN389345 and ABIN2839454) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (PCNA Antikörper (AA 89-117))

IHC (p)

Confocal immunofluorescent analysis of PCNA Antibody (Center) (ABIN389345 and ABIN2839454) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (PCNA Antikörper (AA 89-117))

PCNA Antibody (Center) (ABIN389345 and ABIN2839454) flow cytometric analysis of Hela cells (right histogram) compared to a negative control cell (left histogram). (PCNA Antikörper (AA 89-117))

FACS

4 Abbildungen

Produktnummer ABIN389345

Datenblatt (PDF)

Target Alle PCNA Antikörper anzeigen

PCNA (Proliferating Cell Nuclear Antigen (PCNA))
Bindungsspezifität
16

16

16

15

13

10

8

6

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 89-117
Reaktivität
214

157

156

57

32

28

23

19

19

18

18

16

11

11

7

5

5

4

4

4

4

3

3

3

2

2

2

2

2

1

1

1

1

1
Human
Wirt
134

93

3
Kaninchen
Passende Sekundärantikörper
Klonalität
133

96

1
Polyklonal
Konjugat
119

17

13

8

6

6

5

5

5

5

5

5

5

5

5

4

2

2

1

1

1

1

1

1

1

1
Dieser PCNA Antikörper ist unkonjugiert
Applikation
197

68

66

62

60

50

48

40

34

16

15

12

5

4

3

2

2

2

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Homologie

B, C, Ha, Pr, M, Rat

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This PCNA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the Central region of human PCNA.

Klon

RB17485

Isotyp

Ig Fraction

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PCNA Reaktivität: Human WB, IHC, IHC (p) Wirt: Maus Monoclonal 1H10 unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Target

PCNA (Proliferating Cell Nuclear Antigen (PCNA))

Andere Bezeichnung

PCNA (PCNA Produkte)

Synonyme

PCNAR antikoerper, Pcna/cyclin antikoerper, pcna antikoerper, AO090003000846 antikoerper, 53/13 antikoerper, CG9193 antikoerper, DmPCNA antikoerper, Dmel\\CG9193 antikoerper, MUS209 antikoerper, Mus209 antikoerper, PCNA antikoerper, PCNA/mus209 antikoerper, Pcna antikoerper, dPCNA antikoerper, l(2)02448 antikoerper, l(2)56F antikoerper, l(2)56Fa antikoerper, l(2)s1534 antikoerper, cb16 antikoerper, fb36g03 antikoerper, wu:fa28e03 antikoerper, wu:fb36g03 antikoerper, pcna-A antikoerper, proliferating cell nuclear antigen antikoerper, DNA polymerase III sliding clamp antikoerper, Proliferating cell nuclear antigen antikoerper, Proliferating cell nuclear antigen-like antikoerper, proliferating cell nuclear antigen L homeolog antikoerper, proliferating cell nuclear antigen 1 antikoerper, PCNA antikoerper, Pcna antikoerper, pcna antikoerper, MMP_RS08810 antikoerper, ANI_1_512014 antikoerper, AOR_1_1500154 antikoerper, MGC53867 antikoerper, pcna.L antikoerper, pcna1 antikoerper, LOC106420145 antikoerper, pcn1 antikoerper

Hintergrund

PCNA is found in the nucleus and is a cofactor of DNA polymerase delta. This protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway.

Molekulargewicht

28769

Gen-ID

5111

NCBI Accession

NP_002583, NP_872590

UniProt

P12004

Pathways

Telomere Maintenance, DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Autophagie