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CHEK1 Antikörper (AA 258-287)

Name: CHEK1 Antikörper (AA 258-287)
SKU: ABIN388983
Price: 445.5 EUR
Availability: InStock

CHEK1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB7840 unconjugated

Chk1 Antibody (ABIN388983 and ABIN2839219) western blot analysis in Hela cell line and mouse thymus tissue lysates (35 μg/lane). (CHEK1 Antikörper (AA 258-287))

1 image

Produktnummer ABIN388983

Datenblatt (PDF)

Target Alle CHEK1 Antikörper anzeigen

CHEK1 (Checkpoint Kinase 1 (CHEK1))
Bindungsspezifität
44

29

26

19

14

13

7

6

5

4

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 258-287
Reaktivität
213

118

68

16

9

9

6

5

5

3

3

2

2

1

1
Human, Maus
Wirt
222

14

7

5
Kaninchen
Passende Sekundärantikörper
Klonalität
209

40
Polyklonal
Konjugat
133

13

11

9

9

9

9

8

8

8

5

5

4

4

4

4

4

2
Dieser CHEK1 Antikörper ist unkonjugiert
Applikation
171

87

53

41

40

36

35

17

16

13

10

7

6

3

3

1

1
Western Blotting (WB)

Aufreinigung

This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen

This CHK1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 258-287 amino acids from human CHK1.

Klon

RB7840

Isotyp

Ig Fraction

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anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer286) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer301) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (Middle Region) antibody
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anti-Checkpoint Kinase 1 (CHEK1) (pSer317) antibody
CHEK1 Reaktivität: Human WB, IHC (p), DB Wirt: Kaninchen Polyclonal RB7845-RB18425 unconjugated

anti-Checkpoint Kinase 1 (CHEK1) (pSer280) antibody
CHEK1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

WB: 1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C.

Haltbarkeit

6 months
Target

CHEK1 (Checkpoint Kinase 1 (CHEK1))

Andere Bezeichnung

CHK1 (CHEK1 Produkte)

Synonyme

An08g10320 antikoerper, AO090003000441 antikoerper, CHK1 antikoerper, chk1 antikoerper, C85740 antikoerper, Chk1 antikoerper, rad27 antikoerper, id:ibd2720 antikoerper, zgc:56093 antikoerper, CHEK1 antikoerper, checkpoint kinase 1 antikoerper, serine/threonine-protein kinase chk1 antikoerper, serine/threonine-protein kinase Chk1 antikoerper, CAMK/CAMKL/CHK1 protein kinase Chk1 antikoerper, checkpoint kinase 1 S homeolog antikoerper, CHEK1 antikoerper, ANI_1_2436074 antikoerper, AOR_1_768154 antikoerper, PTRG_04183 antikoerper, SJAG_01680 antikoerper, PAAG_04978 antikoerper, MCYG_03290 antikoerper, VDBG_03742 antikoerper, chek1.S antikoerper, Chek1 antikoerper, chek1 antikoerper

Hintergrund

HRD1 is a ubiquitin ligase whose expression is induced by the unfolded protein response (UPR) following endoplasmic reticulum stress. Expression of HRD1 protects cells from apoptosis by inducing degradation of abnormally processed proteins that accumulate in the endoplasmic reticulum. HRD1 is expressed in many tissues, strongly expressed in brain, pancreas, liver, kidney and skeletal muscle. Amano T, et al. reported that Synoviolin/Hrd1 (expressed in rheumatoid synovium) is a novel causative factor for arthropathy by triggering synovial cell outgrowth through its antiapoptotic effects. HRD1 contains one ring-type zinc finger.

Molekulargewicht

54434

NCBI Accession

NP_001107593, NP_001107594, NP_001231775, NP_001265

UniProt

O14757

Pathways

p53 Signalweg, Apoptose, Zellzyklus, DNA Reparatur