SKP1 Antikörper (AA 58-87)

Produktnummer ABIN388650

Der Kaninchen Polyklonal anti-SKP1 Antikörper (Klon RB9342) (ABIN388650) detektiert spezifisch SKP1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für SKP1 Antikörper (AA 58-87) (ABIN388650)

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Klon: RB9342

Produktdetails anti-SKP1 Antikörper

Bindungsspezifität: AA 58-87

Homologie: B, C, Pr, M, Rat, X

Aufreinigung: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This SKP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-87 amino acids from the Central region of human SKP1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu SKP1

Target: SKP1 (S-Phase Kinase-Associated Protein 1 (SKP1))

Andere Bezeichnung: SKP1

Hintergrund: SKP1A is an F-box protein which functions as a substrate recognition component of the SCF ubiquitin ligase complex. It binds to cyclin F, S-phase kinase-associated protein 2, and other regulatory proteins involved in ubiquitin proteolysis through an F-box motif. SKP1A also collaborates with a network of proteins to control beta-catenin levels and affects the activity level of beta-catenin dependent TCF transcription factors. Studies have also characterized the protein as an RNA polymerase II elongation factor.

Molekulargewicht: 18658

Gen-ID: 6500

NCBI Accession: NP_008861, NP_733779

UniProt: P63208

Pathways: Zellzyklus, Hedgehog Signalweg, Mitotic G1-G1/S Phases