Cadherin 4 Antikörper (N-Term)

Produktnummer ABIN388148

Der Kaninchen Polyklonal Anti-Cadherin 4-Antikörper wurde für WB, IF, FACS und IHC (p) validiert. Er ist geeignet, Cadherin 4 in Proben von Human zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für Cadherin 4 Antikörper (N-Term) (ABIN388148)

Target: Cadherin 4 (CDH4)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cadherin 4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB13654

Produktdetails anti-Cadherin 4 Antikörper

Bindungsspezifität: AA 175-203, N-Term

Homologie: M, Rat

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This CDH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 175-203 amino acids from the N-terminal region of human CDH4.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: IF: 1:10~50. WB: 1:2000. WB: 1:2000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Referenzen für anti-Cadherin 4 Antikörper (ABIN388148)

Li, Takai, Yuge, Furukawa, Tsuno, Tsukamoto, Kong, Moriyama, Narahara: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." in: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).

Details zu Cadherin 4

Target: Cadherin 4 (CDH4)

Andere Bezeichnung: CDH4

Hintergrund: CDH4 is a classical cadherin from the cadherin superfamily. It is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization.

Molekulargewicht: 100281

Gen-ID: 1002

NCBI Accession: NP_001239267, NP_001239268, NP_001785

UniProt: P55283

Pathways: Cell-Cell Junction Organization, Regulation of Cell Size