Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

JAK2 Antikörper (C-Term)

Name: JAK2 Antikörper (C-Term)
SKU: ABIN387982
Price: 434.77 EUR
Availability: InStock

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch JAK2 in WB, FACS und IF. Er zeigt eine Reaktivität gegenüber Human und Maus und wurde in 3+ Publikationen erwähnt.

The anti-JAK2 Pab (ABIN387982 and ABIN2844820) is used in Western blot to detect JAK2 in mouse thymus tissue lysate. (JAK2 Antikörper (C-Term))

JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) flow cytometric analysis of K562 cells (right histogram) compared to a negative control (PBS alone) (left histogram). (JAK2 Antikörper (C-Term))

FACS

Confocal immunofluorescent analysis of JAK2 Antibody (C-term) (ABIN387982 and ABIN2844820) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (JAK2 Antikörper (C-Term))

3 Abbildungen

(3 Referenzen)

Produktnummer ABIN387982

Datenblatt (PDF)

Kurzübersicht für JAK2 Antikörper (C-Term) (ABIN387982)

Target

Alle JAK2 Antikörper anzeigen

JAK2 (Janus Kinase 2 (JAK2))

Reaktivität

Human, Maus

Wirt

Kaninchen

Klonalität

Polyklonal

Konjugat

Dieser JAK2 Antikörper ist unkonjugiert

Applikation

Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon

RB02956

Discover our top product JAK2 Primärantikörper

Bindungsspezifität
30

28

16

16

6

6

6

5

5

4

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1101-1132, C-Term

Aufreinigung

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen

This JAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1101-1132 amino acids from the C-terminal region of human JAK2.

Isotyp

Ig Fraction
anti-Janus Kinase 2 (JAK2) (AA 508-800) antibody
JAK2 Reaktivität: Human WB, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 916-1103) antibody
JAK2 Reaktivität: Ratte WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 Reaktivität: Human, Ratte, Maus, Kaninchen, Zebrafisch (Danio rerio) WB, ELISA, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 745-955) antibody
JAK2 Reaktivität: Human IHC, ELISA, FACS Wirt: Maus Monoclonal 5C12C9 unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr221) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr931) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (pTyr1007), (pTyr1008) antibody
JAK2 Reaktivität: Human WB, IHC, ELISA, IP Wirt: Kaninchen Monoclonal 1A4 unconjugated Recombinant Antibody

anti-Janus Kinase 2 (JAK2) (C-Term) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (AA 1101-1132) antibody
JAK2 Reaktivität: Human, Maus WB, ELISA, FACS, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Janus Kinase 2 (JAK2) (N-Term) antibody
JAK2 Reaktivität: Human, Ratte, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

IF: 1:10~50. WB: 1:1000. FC: 1:10~50

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit

6 months
Feng, Chen, Wang, Cheng, Zou, Zhong, Xu: "Roflumilast reverses polymicrobial sepsis-induced liver damage by inhibiting inflammation in mice." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 97, Issue 9, pp. 1008-1019, (2017) (PubMed).

Zhao, Li, Liao, Luo, Shi, Feng, Chen: "Evodiamine Induces Apoptosis and Inhibits Migration of HCT-116 Human Colorectal Cancer Cells." in: International journal of molecular sciences, Vol. 16, Issue 11, pp. 27411-21, (2015) (PubMed).

Kanda, Watanabe: "Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes." in: Endocrinology, Vol. 148, Issue 5, pp. 2317-25, (2007) (PubMed).
Target

JAK2 (Janus Kinase 2 (JAK2))

Andere Bezeichnung

JAK2

Hintergrund

This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.

Molekulargewicht

130674

Gen-ID

3717

NCBI Accession

NP_004963

UniProt

O60674

Pathways

JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Response to Growth Hormone Stimulus, Positive Regulation of Endopeptidase Activity, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Platelet-derived growth Factor Receptor Signaling, Unfolded Protein Response