The antibody detects: Human TCR, Zap-70 (Mr 70 kDa)
To insure lot-to-lot consistency, each batch of product is tested by ELISA and/or PCFIA assay to conform to the characteristics of a standard reference reagent.
ZAP70
Reaktivität: Human
WB, IHC, IF, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Working Dilution: <= 1 µg/10^6 cells Representative data are included in this product insert.
Each laboratory should determine an optimum working titer for use in its particular application. Other applications have not been tested but use in such assays should not necessarily be excluded.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Handhabung
Each reagent is stable for the period shown on the bottle label if stored as directed.
Lagerung
4 °C
Target
ZAP70
(zeta-Chain (TCR) Associated Protein Kinase 70kDa (ZAP70))
Andere Bezeichnung
ZAP-70
Hintergrund
ZAP 70, also known as TCR associated protein, is a protein tyrosine kinase (PTK) with the primary role of catalyzing the phosphorylation of tyrosine residues in cellular proteins, and thus, contributes significantly to the initiation of cell signaling. ZAP 70 is expressed on T cells and NK cells. The monoclonal antibodies SB70 and SBZAP were generated against a KLH-peptide sequence corresponding to the human ZAP 70 amino acid residues 280-309.