Casein Kinase 1 delta Antikörper (Internal Region)
Kurzübersicht für Casein Kinase 1 delta Antikörper (Internal Region) (ABIN374678)
Target
Alle Casein Kinase 1 delta (CSNK1D) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Sequenz
- C-DREERLRHSR NPATR
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Spezifität
- This antibody reacts to both reported isoforms of Casein kinase I delta.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat, Canine.
Species reactivity (tested):Human. -
Aufreinigung
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
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Immunogen
- Peptide with sequence from the internal region of the protein sequence according to NP_001884.2, NP_620693.1
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Applikationshinweise
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Peptide ELISA: 1/64000. Western Blot: 0.3 - 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 0.5 mg/mL
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Buffer
- Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Casein Kinase 1 delta (CSNK1D) (Casein Kinase 1, delta (CSNK1D))
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Andere Bezeichnung
- Casein Kinase I delta
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Hintergrund
- The casein kinase 1 family of protein kinases is common to all eukaryotic cells, although tissue distribution and subcellular localisation may vary between isoforms. Casein kinase 1 delta has been implicated in the regulation of p53. Upregulation of casein kinase 1 delta expression has been reported in Alzheimer's disease hippocampus and its association with tau-containing bodies suggests that it may play a role in the abnormal phosphorylation of tau.Synonyms: CKI-delta, CKId, CSNK1D
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Molekulargewicht
- 47.3 kDa (NP_001884.2)
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Gen-ID
- 1453, 9606
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UniProt
- P48730
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Pathways
- Hedgehog Signalweg, M Phase
Target
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