GZMB Antikörper (N-Term)
Kurzübersicht für GZMB Antikörper (N-Term) (ABIN372968)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody reacts to Granzyme B.
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Kreuzreaktivität (Details)
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Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. -
Aufreinigung
- Immunoaffinity Chromatography
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Immunogen
- A synthetic peptide from N-terminus of human Granzyme B
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 19-247) antibodyGZMB Reaktivität: Human WB, IHC, ICC, IF (p), mIF Wirt: Kaninchen Monoclonal BLR022E unconjugated Recombinant Antibody
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human WB, IHC Wirt: Maus Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reaktivität: Human WB, IP Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human WB, IHC, IF, IHC (p) Wirt: Maus Monoclonal 4E4 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Maus, Ratte WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reaktivität: Human IHC Wirt: Maus Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reaktivität: Human, Maus WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reaktivität: Human IHC, ELISA Wirt: Maus Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CLB-GB11 unconjugated
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Applikationshinweise
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Immunohistochemistry on paraffin sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 10 mM PBS, pH 7.4, BSA, sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- GZMB (Granzyme B (GZMB))
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Hintergrund
- Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
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Gen-ID
- 3002
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NCBI Accession
- NP_004122
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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