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GZMB Antikörper (N-Term)

GZMB Reaktivität: Human, Maus, Ratte IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN372968
  • Target Alle GZMB Antikörper anzeigen
    GZMB (Granzyme B (GZMB))
    Bindungsspezifität
    • 19
    • 16
    • 13
    • 9
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 123
    • 53
    • 25
    • 10
    • 4
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 78
    • 48
    • 2
    Kaninchen
    Klonalität
    • 76
    • 52
    Polyklonal
    Konjugat
    • 79
    • 11
    • 8
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser GZMB Antikörper ist unkonjugiert
    Applikation
    • 72
    • 42
    • 40
    • 37
    • 17
    • 17
    • 17
    • 14
    • 13
    • 9
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts to Granzyme B.
    Kreuzreaktivität (Details)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    Aufreinigung
    Immunoaffinity Chromatography
    Immunogen
    A synthetic peptide from N-terminus of human Granzyme B
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    Discover our top product GZMB Primärantikörper
  • Applikationshinweise
    Immunohistochemistry on paraffin sections: 10 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    10 mM PBS, pH 7.4, BSA, sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    GZMB (Granzyme B (GZMB))
    Abstract
    GZMB Produkte
    Synonyme
    CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
    Hintergrund
    Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
    Gen-ID
    3002
    NCBI Accession
    NP_004122
    UniProt
    P10144
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose
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