GZMB Antikörper (N-Term)
-
- Target Alle GZMB Antikörper anzeigen
- GZMB (Granzyme B (GZMB))
-
Bindungsspezifität
- N-Term
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser GZMB Antikörper ist unkonjugiert
-
Applikation
- Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Spezifität
- This antibody reacts to Granzyme B.
- Kreuzreaktivität (Details)
-
Species reactivity (expected):Mouse, Rat.
Species reactivity (tested):Human. - Aufreinigung
- Immunoaffinity Chromatography
- Immunogen
- A synthetic peptide from N-terminus of human Granzyme B
- Top Product
- Discover our top product GZMB Primärantikörper
-
-
- Applikationshinweise
-
Immunohistochemistry on paraffin sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- 10 mM PBS, pH 7.4, BSA, sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
-
- Target
- GZMB (Granzyme B (GZMB))
- Abstract
- GZMB Produkte
- Synonyme
- CCPI antikoerper, CGL-1 antikoerper, CGL1 antikoerper, CSP-B antikoerper, CSPB antikoerper, CTLA1 antikoerper, CTSGL1 antikoerper, HLP antikoerper, SECT antikoerper, granzyme B antikoerper, GZMB antikoerper
- Hintergrund
- Granzyme B is a cysteine protease found in the cytoplasmic lysosome-like granules of cytolytic T lymphocytes (CTL) and natural killer (NK) cells and is is required for the induction of target cell lysis. This occurs as part of cell mediated immune responses, and can activate apoptosis in target cells by both caspase dependent and caspase independent mechanisms.Synonyms: CGL1, CSPB, CTLA-1, CTLA1, CTSGL1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Fragmentin-2, GRB, Granzyme-2, Lymphocyte protease, SECT, T-cell serine protease 1-3E
- Gen-ID
- 3002
- NCBI Accession
- NP_004122
- UniProt
- P10144
- Pathways
- Apoptose, Caspase Kaskade in der Apoptose
-