EPAS1 Antikörper (C-Term)
Kurzübersicht für EPAS1 Antikörper (C-Term) (ABIN363383)
Target
Alle EPAS1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Spezifität
- Reacts with mouse, rat, fish and human HIF-2 alpha
-
Kreuzreaktivität (Details)
- Does not cross-react with HIF-1 alpha.
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- Synthetic peptide derived from the C-term domain of mouse/human HIF-2 alpha protein.
-
-
-
-
Applikationshinweise
-
Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
WB1.0 μg/mL - 2.0 μg/mL ChIP1:10-1:500 ELISA 1:100-1:2000 ICC/IF1:100 IHC 1:100 IP5 μg/1 mg lysate -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 1.0 mg/mL
-
Buffer
- PBS, Sodium azide 0.05 %
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- Store at 4°C. Do not freeze.
-
-
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
-
Andere Bezeichnung
- Hypoxia-Inducible Factor 2-alpha
-
Hintergrund
- Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung.
-
Gen-ID
- 2034
-
Pathways
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effekt
Target
-