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HIF1A Antikörper (AA 329-530)

HIF1A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund WB, IHC, IP, IF, ICC Wirt: Maus Monoclonal ESEE122 unconjugated

Image no. 10 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 1 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 2 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 3 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 4 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 5 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 6 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 7 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 8 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

Image no. 9 for anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 329-530) antibody (ABIN363210) (HIF1A Antikörper (AA 329-530))

10 Abbildungen

Produktnummer ABIN363210

Datenblatt (PDF)

Target Alle HIF1A Antikörper anzeigen

HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))
Bindungsspezifität
19

16

16

14

8

7

6

6

6

5

4

4

4

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 329-530
Reaktivität
161

92

84

23

22

20

12

11

9

8

7

6

6

5

4

2

2

2

2

2

1

1

1

1

1

1
Human, Maus, Ratte, Rind (Kuh), Hund
Wirt
152

52

5
Maus
Passende Sekundärantikörper
Klonalität
158

51
Monoklonal
Konjugat
104

24

16

6

5

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
Dieser HIF1A Antikörper ist unkonjugiert
Applikation
166

77

61

53

50

38

38

26

26

25

12

8

7

7

3

3

3

2

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität

Reacts with human HIF-1 alpha

Kreuzreaktivität

Maus, Rind (Kuh)

Kreuzreaktivität (Details)

Cross reacts with proteins from bovine, mouse and rat.

Aufreinigung

Purified (protein G)

Immunogen

Human HIF-1 alpha amino acids 329-530

Klon

ESEE122

Isotyp

IgG1

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anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 703-732), (C-Term) antibody
HIF1A Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 218-506) antibody
HIF1A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 575-826) antibody
HIF1A Reaktivität: Human WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 519-547) antibody
HIF1A Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB14548 unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) antibody
HIF1A Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 1A3 unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 216-336) antibody
HIF1A Reaktivität: Ratte WB, IHC, IP, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 432-528) antibody
HIF1A Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Affe, Schaf, Frettchen WB, IHC, ELISA, IP, IF, ICC, FACS, ChIP, GS Wirt: Maus Monoclonal H1alpha67 unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 728-757) antibody
HIF1A Reaktivität: Human, Maus WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A) (AA 519-547) antibody
HIF1A Reaktivität: Human, Maus WB, IHC, ELISA, IF, FACS Wirt: Kaninchen Polyclonal unconjugated

Applikationshinweise

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC/IF10 μg/mL, IHC1:100-1:5000, IP 1:10-1:500, WB1:500-1:1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Konzentration

1 mg/mL

Buffer

Tris-glycine, 150 mM NaCl, Sodium azide 0.01 %

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

-20 °C/-80 °C

Informationen zur Lagerung

Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Target

HIF1A (Hypoxia Inducible Factor 1, alpha Subunit (Basic Helix-Loop-Helix Transcription Factor) (HIF1A))

Andere Bezeichnung

Hypoxia-Inducible Factor 1-alpha (HIF1A Produkte)

Hintergrund

Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularization, tumor angiogenesis and pathophysiology of ischemic disease. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters.

Gen-ID

3091

UniProt

Q16665

Pathways

Positive Regulation of Peptide Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Transition Metal Ion Homeostasis, Tube Formation, Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals, Warburg Effekt

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