EIF2AK2 Antikörper (AA 449-453)
Kurzübersicht für EIF2AK2 Antikörper (AA 449-453) (ABIN362990)
Target
Alle EIF2AK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 449-453
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Spezifität
- The antibody detects endogenous level of total PKR protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
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Immunogen
- Peptide sequence around AA 449-453 (K-G-T-L-R) derived from Human PKR. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Isotyp
- IgG
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anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 1-100) antibody
EIF2AK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1D11 unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 329-551) antibodyEIF2AK2 Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 6H3A10 unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 1-100) antibodyEIF2AK2 Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1B9 unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 224-502) antibodyEIF2AK2 Reaktivität: Human WB, IHC, IP, ICC, FACS Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 1-100) antibodyEIF2AK2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2C2 unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 117-250) antibodyEIF2AK2 Reaktivität: Human WB, IHC, IF, IP Wirt: Maus Monoclonal 13-PKR unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 11-42) antibodyEIF2AK2 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (AA 519-550) antibodyEIF2AK2 Reaktivität: Human, Maus WB, IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (pThr446) antibodyEIF2AK2 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2) (pThr451) antibodyEIF2AK2 Reaktivität: Human, Maus WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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Immunohistochemistry: 1:50-1:100
Immunofluorescence: 1:100-1:200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- EIF2AK2 (Eukaryotic Translation Initiation Factor 2-alpha Kinase 2 (EIF2AK2))
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Andere Bezeichnung
- PKR
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Hintergrund
- Following activation by double-stranded RNA in the presence of ATP, the kinase becomes autophosphorylated and can catalyze the phosphorylation of the translation initiation factor EIF2S1, which leads to an inhibition of the initiation of protein synthesis. Double-stranded RNA is generated during the course of a viral infection.
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Molekulargewicht
- 68 kDa
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NCBI Accession
- NP_001129
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UniProt
- P19525
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Pathways
- DNA Reparatur, ER-Nucleus Signaling, Hepatitis C
Target
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