JAK1 Antikörper (AA 1020-1024)
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- Target Alle JAK1 Antikörper anzeigen
- JAK1 (Janus Kinase 1 (JAK1))
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Bindungsspezifität
- AA 1020-1024
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser JAK1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Spezifität
- The antibody detects endogenous level of total JAK1 protein.
- Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Peptide sequence around AA 1020-1024 (K-E-Y-Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
- Isotyp
- IgG
- Top Product
- Discover our top product JAK1 Primärantikörper
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- Applikationshinweise
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Western blotting: 1:500-1:1000
Immunohistochemistry: 1:50-1:100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).
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Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).
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- Target
- JAK1 (Janus Kinase 1 (JAK1))
- Andere Bezeichnung
- JAK1 (JAK1 Produkte)
- Synonyme
- JAK1A antikoerper, JAK1B antikoerper, JTK3 antikoerper, AA960307 antikoerper, C130039L05Rik antikoerper, wu:fb93e10 antikoerper, jak1 antikoerper, Janus kinase 1 antikoerper, tyrosine-protein kinase JAK1 antikoerper, JAK1 antikoerper, Jak1 antikoerper, jak1 antikoerper, LOC100286690 antikoerper
- Hintergrund
- Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
- Molekulargewicht
- 130 kDa
- NCBI Accession
- NP_002218
- UniProt
- P23458
- Pathways
- JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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