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JAK1 Antikörper (AA 1020-1024)

JAK1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN362702
  • Target Alle JAK1 Antikörper anzeigen
    JAK1 (Janus Kinase 1 (JAK1))
    Bindungsspezifität
    • 16
    • 16
    • 12
    • 10
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1020-1024
    Reaktivität
    • 109
    • 83
    • 63
    • 4
    • 4
    • 2
    • 2
    • 2
    Human, Maus, Ratte
    Wirt
    • 87
    • 28
    • 1
    • 1
    Kaninchen
    Klonalität
    • 81
    • 36
    Polyklonal
    Konjugat
    • 53
    • 8
    • 7
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser JAK1 Antikörper ist unkonjugiert
    Applikation
    • 76
    • 38
    • 27
    • 21
    • 17
    • 14
    • 13
    • 11
    • 10
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous level of total JAK1 protein.
    Aufreinigung
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
    Immunogen
    Peptide sequence around AA 1020-1024 (K-E-Y-Y-T) derived from Human JAK1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Isotyp
    IgG
    Top Product
    Discover our top product JAK1 Primärantikörper
  • Applikationshinweise
    Western blotting: 1:500-1:1000
    Immunohistochemistry: 1:50-1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • Liu, Huang, Zeng, Chen, Huang, Guo, Liu, Xu, Mo, Li: "Down-regulation of JAK1 by RNA interference inhibits growth of the lung cancer cell line A549 and interferes with the PI3K/mTOR pathway." in: Journal of cancer research and clinical oncology, Vol. 137, Issue 11, pp. 1629-40, (2011) (PubMed).

  • Target
    JAK1 (Janus Kinase 1 (JAK1))
    Andere Bezeichnung
    JAK1 (JAK1 Produkte)
    Synonyme
    JAK1A antikoerper, JAK1B antikoerper, JTK3 antikoerper, AA960307 antikoerper, C130039L05Rik antikoerper, wu:fb93e10 antikoerper, jak1 antikoerper, Janus kinase 1 antikoerper, tyrosine-protein kinase JAK1 antikoerper, JAK1 antikoerper, Jak1 antikoerper, jak1 antikoerper, LOC100286690 antikoerper
    Hintergrund
    Tyrosine kinase of the non-receptor type, involved in the IFN-a/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor.
    Molekulargewicht
    130 kDa
    NCBI Accession
    NP_002218
    UniProt
    P23458
    Pathways
    JAK-STAT Signalweg, RTK Signalweg, Interferon-gamma Pathway, Hepatitis C, Toll-Like Receptors Cascades, Unfolded Protein Response
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