NEFL Antikörper

Produktnummer ABIN361353

Dieses Anti-NEFL-Antikörper ist ein Huhn Polyklonal-Antikörper zur Detektion von NEFL in WB und IF. Geeignet für Rind (Kuh).

Kurzübersicht für NEFL Antikörper (ABIN361353)

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Reaktivität: Rind (Kuh)

Wirt: Huhn

Klonalität: Polyklonal

Konjugat: Dieser NEFL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NEFL Antikörper

Spezifität: Specific for the ~68k Neurofilament L protein in Western blots and works well on frozen sections, cells in tissue culture and on mildly formalin fixed histological sections.

Kreuzreaktivität: Huhn, Rind (Kuh), Human, Maus, Ratte (Rattus)

Aufreinigung: Total IgY fraction

Immunogen: Preparation of bovine spinal cord NF-L

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:10,000 IF: 1:5,000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: total IgY fraction in PBS + 10 mM Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu NEFL

Target: NEFL (Neurofilament, Light Polypeptide (NEFL))

Andere Bezeichnung: NEFL

Hintergrund: Neurofilaments are the 10nm or intermediate filament proteins found specifically in neurons, and are composed predominantly of three major proteins called NF-L, NF-M and NF-H (1). NF-L is the neurofilament light or low molecular weight polypeptide and runs on SDS-PAGE gels at about 68kDa. Antibodies to NF-L are useful for identifying neuronal cells and their processes in tissue sections and in tissue culture. Mutations in the protein coding region of the human NF-L gene cause some forms of Charcot-Marie-Tooth disease (2). Anti-Neurofilament L Western blot of rat cortex lysate showing specific immunolableing of the ~ 68k NF-L protein.

Molekulargewicht: '68 kDa

Gen-ID: 4747

UniProt: P02548