NEFL Antikörper (AA 400-543)
Kurzübersicht für NEFL Antikörper (AA 400-543) (ABIN3020809)
Target
Alle NEFL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 400-543
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Sequenz
- LSFTSVGSIT SGYSQSSQVF GRSAYGGLQT SSYLMSTRSF PSYYTSHVQE EQIEVEETIE AAKAEEAKDE PPSEGEAEEE EKDKEEAEEE EAAEEEEAAK EESEEAKEEE EGGEGEEGEE TKEAEEEEKK VEGAGEEQAA KKKD
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 400-543 of human Neurofilament L (NP_006149.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid freeze / thaw cycles
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Andere Bezeichnung
- NEFL
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Hintergrund
- Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.,NEFL,CMT1F,CMT2E,NF-L,NF68,NFL,PPP1R110,Signal Transduction,Cell Biology & Developmental Biology,Cell Adhesion,Cytoskeleton,Intermediate Filaments,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Neural Stem Cell marker,Neuron marker,Axon marker,NEFL
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Molekulargewicht
- 61 kDa
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Gen-ID
- 4747
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UniProt
- P07196
Target
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