Der Maus Monoklonal anti-NEFL Antikörper (Klon 1H3) (ABIN1108416) detektiert spezifisch NEFL in WB, IF, FACS, IHC (p) und EIA.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1.0 mg/mL
Buffer
PBS, 0.05 % sodium azide, 0,5 % BSA
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Target
NEFL
(Neurofilament, Light Polypeptide (NEFL))
Andere Bezeichnung
Neurofilament L (68kDa)
Hintergrund
Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.Synonyms: 68 kDa neurofilament protein, NEFL, NF-L, NF68, Neurofilament L