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PIK3R1 Antikörper (Tyr580)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PIK3R1 in WB und IHC (p). Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN360457

Kurzübersicht für PIK3R1 Antikörper (Tyr580) (ABIN360457)

Target

Alle PIK3R1 (PI3K p85a) Antikörper anzeigen
PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

Reaktivität

  • 134
  • 94
  • 70
  • 17
  • 17
  • 8
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Human

Wirt

  • 116
  • 31
Kaninchen

Klonalität

  • 99
  • 48
Polyklonal

Konjugat

  • 82
  • 10
  • 8
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Dieser PIK3R1 Antikörper ist unkonjugiert

Applikation

  • 117
  • 61
  • 45
  • 28
  • 20
  • 19
  • 17
  • 17
  • 13
  • 8
  • 7
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 19
    • 15
    • 15
    • 10
    • 9
    • 9
    • 7
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Tyr580

    Spezifität

    This antibody reacts to PIK3R1.

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y580 of human PIK3R1.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    PIK3R1 (PI3K p85a) (Phosphoinositide 3 Kinase, p85 alpha (PI3K p85a))

    Andere Bezeichnung

    PIK3R1 / GRB1

    Hintergrund

    Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance.Synonyms: PI3-kinase subunit p85-alpha, PI3K regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit alpha

    Gen-ID

    5295, 9606

    UniProt

    P27986

    Pathways

    T-Zell Rezeptor Signalweg, Response to Growth Hormone Stimulus, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Hepatitis C, Protein targeting to Nucleus, VEGF Signaling, BCR Signaling, Warburg Effekt
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