KIT Antikörper (N-Term)

Produktnummer ABIN359890

Produktdetails anti-KIT Antikörper

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KIT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to c-Kit.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human KIT.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu KIT

Target: KIT (Mast/stem Cell Growth Factor Receptor (KIT))

Andere Bezeichnung: CD117 / C-Kit (KIT Produkte)

Synonyme: C-Kit antikoerper, CD117 antikoerper, PBT antikoerper, SCFR antikoerper, Bs antikoerper, Fdc antikoerper, Gsfsco1 antikoerper, Gsfsco5 antikoerper, Gsfsow3 antikoerper, SCO1 antikoerper, SCO5 antikoerper, SOW3 antikoerper, Ssm antikoerper, Tr-kit antikoerper, W antikoerper, c-KIT antikoerper, c-kit antikoerper, MGF antikoerper, KIT antikoerper, C-KIT antikoerper, kit antikoerper, receptor antikoerper, sparse antikoerper, Xkl-1 antikoerper, kit-a antikoerper, kit-b antikoerper, kl1-A antikoerper, krk1 antikoerper, pbt antikoerper, scfr antikoerper, KIT proto-oncogene receptor tyrosine kinase antikoerper, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog a antikoerper, KIT proto-oncogene receptor tyrosine kinase S homeolog antikoerper, KIT antikoerper, Kit antikoerper, kita antikoerper, kit antikoerper, kit.S antikoerper

Hintergrund: KIT encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. KIT is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in KIT are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism.Synonyms: KIT, Mast/stem cell growth factor receptor, Proto-Oncogene Tyrosine-Protein Kinase, SCFR

Gen-ID: 3815, 5874

UniProt: P10721

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Sensory Perception of Sound, Stem Cell Maintenance, Production of Molecular Mediator of Immune Response, Regulation of long-term Neuronal Synaptic Plasticity