EPH Receptor B4 Antikörper
Kurzübersicht für EPH Receptor B4 Antikörper (ABIN359817)
Target
Alle EPH Receptor B4 (EPHB4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- This antibody reacts to EphB4.
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Aufreinigung
- Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS
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Immunogen
- This antibody is generated from rabbits immunized with human recombinant EphB4 protein.
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Isotyp
- Ig Fraction
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Applikationshinweise
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ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.25 mg/mL
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Buffer
- PBS with 0.09 % (W/V) sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- EPH Receptor B4 (EPHB4)
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Andere Bezeichnung
- EPHB4
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Hintergrund
- Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. EphB4 binds to ephrin-B2 and plays an essential role in vascular development.Synonyms: Ephrin type-B receptor 4, HTK, TYRO11, Tyrosine-protein kinase TYRO11, Tyrosine-protein kinase receptor HTK
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Gen-ID
- 2050, 9606
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UniProt
- P54760
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Pathways
- RTK Signalweg
Target
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