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Paxillin Antikörper (pTyr118)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Paxillin in WB, IHC (p) und EIA. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN359002

Kurzübersicht für Paxillin Antikörper (pTyr118) (ABIN359002)

Target

Alle Paxillin (PXN) Antikörper anzeigen
Paxillin (PXN)

Reaktivität

  • 215
  • 109
  • 77
  • 17
  • 8
  • 8
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Wirt

  • 209
  • 27
  • 1
Kaninchen

Klonalität

  • 186
  • 51
Polyklonal

Konjugat

  • 128
  • 10
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
Dieser Paxillin Antikörper ist unkonjugiert

Applikation

  • 170
  • 65
  • 48
  • 41
  • 40
  • 27
  • 25
  • 24
  • 24
  • 18
  • 14
  • 7
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Bindungsspezifität

    • 32
    • 32
    • 22
    • 16
    • 9
    • 9
    • 9
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr118

    Spezifität

    This Paxillin antibody reacts with Paxillin pTyr118.

    Aufreinigung

    Protein A column, followed by peptide affinity purification

    Immunogen

    This Paxillin antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y118 of human PXN.

    Isotyp

    Ig Fraction
  • Applikationshinweise

    ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Immunohistochemistry: 1/10 - 1/50.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    0.25 mg/mL

    Buffer

    PBS with 0.09 % (W/V) sodium azide

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freezing and thawing.

    Lagerung

    4 °C/-20 °C

    Informationen zur Lagerung

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target

    Paxillin (PXN)

    Andere Bezeichnung

    Paxillin / PXN

    Hintergrund

    Paxillin is a 64 kDa cytoskeletal adapter protein involved in organisation and function of focal adhesions, which are critical to cell adhesion and migration. This in turn plays a role in a wide variety of processes including embryogenesis, organogenesis, wound repair, inflammation and cancer. Paxillin contains LD motifs, LIM domains, SH3 and SH2 binding domains that serve as docking sites for cytoskeletal proteins, tyrosine kinases (e.g., FAK, Pyk 2, Src), serine/threonine kinases, GTPase activating proteins and other adaptor proteins (e.g., Actin, Vinculin, Crk).Synonyms: FLJ16691

    Gen-ID

    5829, 9606

    UniProt

    P49023

    Pathways

    MAPK Signalweg, EGFR Signaling Pathway, Response to Growth Hormone Stimulus, Cell-Cell Junction Organization, Maintenance of Protein Location, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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