CDK7 Antikörper (pThr170)

Produktnummer ABIN358107

Produktdetails anti-CDK7 Antikörper

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Bindungsspezifität: pThr170

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects CDK7 pThr170. Predicted to cross react with Mouse (100 % Antigen Homology).

Aufreinigung: Protein G Affinity Chromatography. Then, the antibody fraction is peptide affinity purified in a 2-step procedure with control and phosphorylated peptides. The phospho-specific antibody is eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T170 of human CDK7.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu CDK7

Target: CDK7 (Cyclin-Dependent Kinase 7 (CDK7))

Andere Bezeichnung: CDK7 (CDK7 Produkte)

Synonyme: CAK1 antikoerper, CDKN7 antikoerper, HCAK antikoerper, MO15 antikoerper, STK1 antikoerper, p39MO15 antikoerper, AI323415 antikoerper, AI528512 antikoerper, C230069N13 antikoerper, Cdkn7 antikoerper, Crk4 antikoerper, CD 7 antikoerper, CDK7 antikoerper, CG3319 antikoerper, DmCDK7 antikoerper, DmCdk7 antikoerper, DmMO15 antikoerper, DmMo15 antikoerper, Dmcdk7 antikoerper, Dmel\\CG3319 antikoerper, Mo15 antikoerper, cdk-7 antikoerper, cdk7 antikoerper, dCdk7 antikoerper, p40[MO15] antikoerper, p40MO15 antikoerper, stk1 antikoerper, zgc:85821 antikoerper, cak1 antikoerper, cdkn7 antikoerper, p39mo15 antikoerper, cyclin dependent kinase 7 antikoerper, cyclin-dependent kinase 7 antikoerper, Cyclin-dependent kinase 7 antikoerper, cyclin-dependent kinase 7 L homeolog antikoerper, CDK7 antikoerper, Cdk7 antikoerper, cdk7.L antikoerper, cdk7 antikoerper

Hintergrund: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.Synonyms: 39 kDa protein kinase, CAK1, CDK-activating kinase, Cell division protein kinase 7, P39 Mo15, STK1, TFIIH basal transcription factor complex kinase subunit

Molekulargewicht: 39038 Da

Gen-ID: 1022, 9606

UniProt: P50613

Pathways: Zellzyklus, DNA Reparatur, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase