CDCA8 Antikörper (Center)

Produktnummer ABIN356941

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch CDCA8 in WB, IHC (p) und EIA. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CDCA8 Antikörper (Center) (ABIN356941)

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDCA8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Produktdetails anti-CDCA8 Antikörper

Bindungsspezifität: Center

Spezifität: This antibody detects CDCA8 at center.

Aufreinigung: Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human CDCA8.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Western blotting 1: 100 - 1: 500. Immunohistochemistry 1: 10 - 1: 50.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Details zu CDCA8

Target: CDCA8 (Cell Division Cycle Associated 8 (CDCA8))

Andere Bezeichnung: CDCA8 / Borealin

Hintergrund: CDCA8 is a component of the chromosomal passenger complex (CPC) required for stability of the bipolar mitotic spindle. The CPC complex, a key regulator of mitosis, has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 may be required to direct the CPC to centromeric DNA.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B

Molekulargewicht: 31323 Da

Gen-ID: 55143, 9606

UniProt: Q53HL2

Pathways: Zellzyklus, M Phase