CDCA8 Antikörper (N-Term)
Kurzübersicht für CDCA8 Antikörper (N-Term) (ABIN1449290)
Target
Alle CDCA8 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-280, N-Term
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Spezifität
- This antibody reacts with Borealin (35 kDa).
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human
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Aufreinigung
- Protein A agarose
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Immunogen
- Recombinant full-length human Borealin (1-280 aa)
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- PBS containing 50 % glycerol, pH 7.2. No preservative is contained.
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Konservierungsmittel
- Without preservative
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Upon receipt, store (in aliqouts) at -20 °C.
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- CDCA8 (Cell Division Cycle Associated 8 (CDCA8))
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Andere Bezeichnung
- CDCA8 / Borealin
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Hintergrund
- Borealin is a subunit of the chromosomal passenger complex (CPC), which is necessary for chromosome segregation and cytokinesis. While CPC shows a dynamic localization pattern during mitosis, Borealin and survivin, another subunit of CPC is essential to localize CPC at centromare from prophase to anaphase. It is thought that Borealin and survivin recruit aurora B, a kinase subunit of CPC, to inner centromare to allow phosphorylating appropriate substrates.Synonyms: Cell division cycle-associated protein 8, Dasra-B, PESCRG3, Pluripotent embryonic stem cell-related gene 3 protein, hDasra-B
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Gen-ID
- 55143
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NCBI Accession
- NP_060571
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UniProt
- Q53HL2
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Pathways
- Zellzyklus, M Phase
Target
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