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NGFR Antikörper

Dieses Maus Monoklonal-Antikörper erkennt spezifisch NGFR in WB, IHC und ELISA. Er zeigt eine Reaktivität gegenüber Ratte.
Produktnummer ABIN350707

Kurzübersicht für NGFR Antikörper (ABIN350707)

Target

Alle NGFR Antikörper anzeigen
NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität

  • 208
  • 62
  • 54
  • 39
  • 30
  • 28
  • 27
  • 22
  • 12
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
Ratte

Wirt

  • 110
  • 104
  • 4
  • 1
Maus

Klonalität

  • 143
  • 76
Monoklonal

Konjugat

  • 97
  • 18
  • 12
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser NGFR Antikörper ist unkonjugiert

Applikation

  • 116
  • 93
  • 89
  • 59
  • 43
  • 43
  • 28
  • 27
  • 21
  • 17
  • 15
  • 15
  • 12
  • 8
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA
  • Verwendungszweck

    Mouse monoclonal antibody to rat p75NTR (MC192)

    Spezifität

    Specific for rat p75NTR.

    Kreuzreaktivität

    Ratte

    Aufreinigung

    Affinity purified

    Immunogen

    Nerve growth factor receptor (TNFR superfamily member 16)
  • Applikationshinweise

    WB IHC ELISA. A working concentration of 5-15 μg,ml is recommended. This antibody is suitable for use in paraformaldehyde fixed alcohol fixed,paraffin-embedded sections. The optimal working solution should be determined by the end user.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

    Handhabung

    Avoid freeze and thaw cycles.

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

    Haltbarkeit

    12 months
  • Target

    NGFR (Nerve Growth Factor Receptor (NGFR))

    Andere Bezeichnung

    p75NTR

    Hintergrund

    FUNCTION: Low affinity receptor which can bind to NGF BDNF NT-3 and NT-4. Can mediate cell survival as well as cell death of neural cells. SUBUNIT: Homodimer, disulfide-linked. Interacts with p75NTR-associated cell death executor. Interacts with NGFRAP1/BEX3. Interacts with TRAF2 TRAF4 TRAF6 PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1. SUBCELLULAR LOCATION: Membrane, Single-pass type I membrane protein.

    Pathways

    NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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