NGFR Antikörper

Produktnummer ABIN2855341

Produktdetails anti-NGFR Antikörper

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NGFR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Rabbit Polyclonal antibody to p75 NGF Receptor (nerve growth factor receptor (TNFR superfamily, member 16))
p75 NGF Receptor antibody

Aufreinigung: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein encompassing a sequence within the center region of human p75 NGF Receptor / CD271. The exact sequence is proprietary.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: Assay dependent. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

Kommentare:

Positive Control: PC-12 , mouse brain , rat brain

Validation: Orthogonal

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.43 mg/mL

Buffer: 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.

Referenzen für anti-NGFR Antikörper (ABIN2855341)

Zhang, Zhang, Luo, Yan, Niibe, Egusa, Zhang, Xie, Jiang: "Investigate the Odontogenic Differentiation and Dentin-Pulp Tissue Regeneration Potential of Neural Crest Cells." in: Frontiers in bioengineering and biotechnology, Vol. 8, pp. 475, (2020) (PubMed).

Details zu NGFR

Target: NGFR (Nerve Growth Factor Receptor (NGFR))

Andere Bezeichnung: nerve growth factor receptor (NGFR Produkte)

Synonyme: ngfr antikoerper, wu:fb38c02 antikoerper, wu:fc10h01 antikoerper, CD271 antikoerper, Gp80-LNGFR antikoerper, TNFRSF16 antikoerper, p75(NTR) antikoerper, p75NTR antikoerper, LNGFR antikoerper, RNNGFRR antikoerper, Tnfrsf16 antikoerper, p75 antikoerper, NRH1b antikoerper, fullback antikoerper, nrh1 antikoerper, p75ntr antikoerper, tnfrsf16 antikoerper, p75NGFR antikoerper, nerve growth factor receptor antikoerper, neurotrophin receptor associated death domain antikoerper, nerve growth factor receptor S homeolog antikoerper, nerve growth factor receptor (TNFR superfamily, member 16) antikoerper, NGFR antikoerper, nradd antikoerper, Ngfr antikoerper, ngfr.S antikoerper

Hintergrund: Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain.

Cellular Localization: Membrane, Single-pass type I membrane protein

Molekulargewicht: 45 kDa

Gen-ID: 4804

UniProt: P08138

Pathways: NF-kappaB Signalweg, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding