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Dynactin 1 Antikörper (AA 120-170)

DCTN1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN350280
  • Target Alle Dynactin 1 (DCTN1) Antikörper anzeigen
    Dynactin 1 (DCTN1)
    Bindungsspezifität
    • 15
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 120-170
    Reaktivität
    • 55
    • 23
    • 17
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 38
    • 14
    • 3
    • 1
    Kaninchen
    Klonalität
    • 42
    • 14
    Polyklonal
    Konjugat
    • 35
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Dynactin 1 Antikörper ist unkonjugiert
    Applikation
    • 47
    • 17
    • 13
    • 13
    • 12
    • 9
    • 8
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    Specific for DCTN1.
    Kreuzreaktivität
    Human, Maus, Ratte
    Kreuzreaktivität (Details)
    Other species not yet tested.
    Aufreinigung
    IgG
    Immunogen
    A synthetic peptide from AA 120-170 of human DCTN1 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in rat and moue.
    Isotyp
    IgG
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    Discover our top product DCTN1 Primärantikörper
  • Applikationshinweise
    IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.
    Handhabung
    Avoid freeze and thaw cycles.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
    Haltbarkeit
    12 months
  • Target
    Dynactin 1 (DCTN1)
    Andere Bezeichnung
    DCTN1 (DCTN1 Produkte)
    Synonyme
    DAP-150 antikoerper, DP-150 antikoerper, P135 antikoerper, Chip150 antikoerper, DCTN1 antikoerper, DKFZp469C1813 antikoerper, AL022633 antikoerper, Glued antikoerper, p150 antikoerper, p150 antikoerper, CG9206 antikoerper, DYNA_DROME antikoerper, Dmel\\CG9206 antikoerper, FCP-D antikoerper, Glu antikoerper, P150 antikoerper, P150[Glued] antikoerper, p150/Glued antikoerper, p150/glued antikoerper, p150[Glued] antikoerper, p150[glued] antikoerper, t1 antikoerper, Dynactin-1 antikoerper, glued antikoerper, dynactin subunit 1 antikoerper, dynactin 1 antikoerper, Dynactin 1, p150 subunit antikoerper, dynactin subunit 1 L homeolog antikoerper, DCTN1 antikoerper, Dctn1 antikoerper, DCTN1-p150 antikoerper, dctn1.L antikoerper
    Hintergrund
    FUNCTION: Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles. SUBUNIT: Large macromolecular complex of at least 10 components, p150(glued) binds directly to microtubules and to cytoplasmic dynein. Interacts with the C-terminus of MAPRE1, MAPRE2 and MAPRE3. SUBCELLULAR LOCATION: Cytoplasm. Cytoplasm, cytoskeleton. TISSUE SPECIFICITY: Brain. DISEASE: Defects in DCTN1 are the cause of progressive lower motor neuron disease. PLMND is a progressive dominant disease that has no sensory symptoms.,Signal Transduction,DAP-150, DP-150, p150-glued,p135, Dynactin subunit 1, 150 kDa dynein-associated polypeptide
    UniProt
    Q14203
    Pathways
    M Phase, ER-Nucleus Signaling
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