IL-6 Receptor Antikörper (Extracellular Domain)

Produktnummer ABIN327368

Der Ratte Monoklonal Anti-IL-6 Receptor-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, IL-6 Receptor in Proben von Maus zu detektieren.

Kurzübersicht für IL-6 Receptor Antikörper (Extracellular Domain) (ABIN327368)

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-6 Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL-6 Receptor Antikörper

Bindungsspezifität: Extracellular Domain

Spezifität: Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.

Aufreinigung: Protein G purified

Immunogen: NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, WB

Usage: Western Blot: This antibody can be used at 1-2 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: 200 μL sterile PBS

Konzentration: Lot specific

Buffer: Lyophilized from PBS,  pH 7.4, 5 % trehalose.

Handhabung: Avoid freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze-thaw cycles.

Details zu IL-6 Receptor

Target: IL-6 Receptor (IL6R) (Interleukin 6 Receptor (IL6R))

Andere Bezeichnung: IL6R / IL6 Receptor

Hintergrund: Name/Gene ID: IL6R
Family: Interleukin

Synonyms: IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ

Gen-ID: 3570

UniProt: P08887

Pathways: JAK-STAT Signalweg, Autophagie, Growth Factor Binding, Cancer Immune Checkpoints