Glucagon Antikörper (N-Term)

Produktnummer ABIN318563

Der Ziege Polyklonal Anti-Glucagon-Antikörper wurde für EIA validiert. Er ist geeignet, Glucagon in Proben von Human und Schwein zu detektieren.

Kurzübersicht für Glucagon Antikörper (N-Term) (ABIN318563)

Target: Glucagon (GCG)

Reaktivität: Human, Schwein

Wirt: Ziege

Klonalität: Polyklonal

Konjugat: Dieser Glucagon Antikörper ist unkonjugiert

Applikation: Enzyme Immunoassay (EIA)

Produktdetails anti-Glucagon Antikörper

Bindungsspezifität: AA 1-12, N-Term

Spezifität: This antibody recognises the pancreatic polypeptide hormone Glucagon, whose actions are antagonistic to insulin. Tumours arising from glucagon producing cells are termed glucagonomas, and this antibody may be useful in identifying such tumours.

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein G

Immunogen: Porcine glucagon, amino acids 1-12, conjugated with bTG.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 5.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Glucagon

Target: Glucagon (GCG)

Andere Bezeichnung: Glucagon

Hintergrund: Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.Synonyms: GCG

Gen-ID: 2641

NCBI Accession: NP_002045

UniProt: P01275

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling