Glucagon Antikörper (AA 19-29)
Kurzübersicht für Glucagon Antikörper (AA 19-29) (ABIN318560)
Target
Alle Glucagon (GCG) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 19-29
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Spezifität
- This antibody is specific for the C terminal of Glucagon, a linear peptide of 29 amino acids. Its primary sequence is highly conserved among vertebrates.
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Aufreinigung
- Purified IgG prepared by affinity chromatography on Protein G
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Immunogen
- Glucagon amino acids 19-29, prepared by enzymatic cleavage of Porcine glucagon, conjugated with bovine thyroglobulin carrier protein.
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Isotyp
- IgG
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Applikationshinweise
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Radioimmunoassays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Phosphate buffered saline containing 0.09 % Sodium Azide (NaN3) 1 % Bovine Serum Albumin
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- Glucagon (GCG)
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Andere Bezeichnung
- Glucagon
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Hintergrund
- Glucagon is a hormone that is secreted by alpha cells in the pancreas. Glucagon antagonizes insulin by converting glycogen to glucose in the liver and increasing blood sugar levels. Glucagon-like peptide 1 (GLP1), Glucagon-like peptide 2 (GLP2), VIP (vasoactive intestinal peptide) and PACAP (pituitary adenylate cyclase activating polypeptide) are in the glucagons hormone family. GLP1 is a transmitter in the central nervous system that regulates feeding and drinking behavior. GLP2 stimulates intestinal epithelial growth.Synonyms: GCG
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Gen-ID
- 2641
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NCBI Accession
- NP_002045
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UniProt
- P01275
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Pathways
- Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Negative Regulation of intrinsic apoptotic Signaling
Target
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