This antibody specifically recognises interleukin-1 alpha (IL-1 alpha). Clone Flo1 can be used in functional studies to neutralize the activity of 125pg/mL of recombinant mouse IL-1 alpha by 95 % , as tested using mouse D10(N4)M T-helper cells.
IL1A
Reaktivität: Human
IHC, ELISA
Wirt: Maus
Monoclonal
2A2B3
unconjugated
Applikationshinweise
ELISA. Functional Assays: 50g/mL. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Konzentration
1.0mg/mL
Buffer
Phosphate buffered saline
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Store the antibody at -20 °C. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Haltbarkeit
12 months
Target
IL1A
(Interleukin 1 alpha (IL1A))
Andere Bezeichnung
Interleukin-1 alpha / IL-1A
Hintergrund
IL-1 alpha is a pleiotropic pro-inflammatory cytokine and member of the IL-1 superfamily, secreted by activated macrophages and monocytes, which mediates a wide range of immune and inflammatory responses. IL-1 alpha and closely related IL-1 beta, are both involved in haematopoiesis and exhibit many identical immunomodulatory properties, binding to the same type I interleukin-1 receptor, also known as CD121a.Synonyms: Hematopoietin-1, IL-1 alpha, IL1A, IL1F1