Complement Factor B Antikörper (Fragment Bb)

Produktnummer ABIN317054

Der Maus Monoklonal Anti-Complement Factor B-Antikörper wurde für WB, FACS und EIA validiert. Er ist geeignet, Complement Factor B in Proben von Human zu detektieren.

Kurzübersicht für Complement Factor B Antikörper (Fragment Bb) (ABIN317054)

Target: Complement Factor B (CFB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Complement Factor B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)

Klon: 032B-22-1-X

Produktdetails anti-Complement Factor B Antikörper

Bindungsspezifität: Fragment Bb

Spezifität: This antibody recognises a neoantigen of the Bb fragment of complement factor B.

Produktmerkmale: Synonyms: Properdin factor B, C3/C5 convertase, PBF2, CFB, BF, BFD, Glycine-rich beta glycoprotein

Aufreinigung: Purified IgG prepared by affinity chromatography on Protein A

Immunogen: Binds neoantigen of fragment Bb from human complement factor B.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Flow Cytometry. ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0mg/mL

Buffer: Borate buffered saline pH 8.2 - 8.4 containing 0.02 % Sodium Azide (NaN3)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request) This product containsSodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled bytrained staff only.

Haltbarkeit: 12 months

Details zu Complement Factor B

Target: Complement Factor B (CFB)

Andere Bezeichnung: Complement Factor B

Hintergrund: Factor B is present in blood serum. C3b associates with complement factor B, inducing conformational change. This enables complement factor D to cleave the N-terminal of complement factor B (the Ba subunit) leaving the 63 kDa Bb subunit associated with C3b and forming C3 convertase. Subunit Bb is involved in the proliferation of preactivated B lymphocytes. Conversely, Ba inhibits lymphocyte proliferation.Synonyms: BF, BFD, C3/C5 convertase, CFB, Glycine-rich beta glycoprotein, PBF2, Properdin factor B

Gen-ID: 629

UniProt: P00751

Pathways: Komplementsystem, Proton Transport, Ribonucleoside Biosynthetic Process