GLI1 Antikörper

Produktnummer ABIN307152

Der Kaninchen Polyklonal anti-GLI1 Antikörper (ABIN307152) detektiert spezifisch GLI1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für GLI1 Antikörper (ABIN307152)

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GLI1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GLI1 Antikörper

Verwendungszweck: Rabbit anti Human Zinc Finger Protein GLI1

Kreuzreaktivität: Human

Produktmerkmale: Zinc Finger Protein GLI1 is a member of the Kruppel family of zinc finger proteins. It is thought that it may regulate the transcription of specific genes during normal development and may play a role in craniofacial development and digital development. It also may be involved in the development of the central nervous system and gastrointestinal tract. This protein mediates SHH signaling and thus cell proliferation and differentiation. It has been localized to the cytoplasm and nucleus. It is tethered in the cytoplasm by binding to SUFU and activation and translocalization to the nucleus is promoted by interation with STK36. Protein expression is amplified in glioblastoma cells. Defects in the GLI1 protein may be a cause of breast cancer.

Aufreinigung: Ammonium Sulfate Precipitation

Immunogen: Synthetic peptide derived from human zinc finger protein GLI1.

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu GLI1

Target: GLI1 (Zinc Finger Protein GLI1 (GLI1))

Andere Bezeichnung: Zinc Finger Protein GLI1

Hintergrund: Glioma-associated oncogene, Oncogene GLI

UniProt: P08151

Pathways: Hedgehog Signalweg, Dopaminergic Neurogenesis