CDC25A Antikörper
Kurzübersicht für CDC25A Antikörper (ABIN306562)
Target
Alle CDC25A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Mouse anti Human CDC25A
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Produktmerkmale
- The immunogen for the anti CDC25A was a purified recombinant CDC25A protein recognizing a 65kD protein. In the cell cycle of eukaryotes the M phase is initiated by maturation promoting factor (MPF), a protein kinase complex consisting of p34 cdc2, cyclin B, and p13. The activity of this complex is controlled by multiple levels of phosphorylation and dephosphorylation of the catalytic p34cdc2 component. CDC25A and CDC25B arep34cdc2 tyrosine phosphates. Dephosphorylation of p34cdc2 by these CDC25 proteins activates the MPF complex, initiating mitosis. Although expressed throughout the cell cycle, peak expression of CDC25A is in G1 of the cell cycle.
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Aufreinigung
- Protein A/G Chromatography
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Isotyp
- IgG2a
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Applikationshinweise
- Western Blot, Immunoprecipitation at 1-10 μg/mL
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/ml
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))
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Andere Bezeichnung
- CDC25A
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Hintergrund
- Dual specificity phosphatase Cdc25A, M-phase inducer phosphatase 1, MPIP1,
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UniProt
- P30304
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases, M Phase
Target
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