TPP1 Antikörper (Middle Region)

Produktnummer ABIN3044554

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TPP1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TPP1 Antikörper (Middle Region) (ABIN3044554)

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TPP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TPP1 Antikörper

Bindungsspezifität: AA 227-261, Middle Region

Verwendungszweck: Anti-TPP1 Antibody

Sequenz: CAQFLEQYFH DSDLAQFMRL FGGNFAHQAS VARVV

Kreuzreaktivität (Details): No cross-reactivity with other proteins.

Produktmerkmale: Anti-TPP1 Antibody (ABIN3044554). Tested in IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TPP1, different from the related mouse sequence by six amino acids, and from the related rat sequence by five amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Details zu TPP1

Target: TPP1 (Tripeptidyl Peptidase I (TPP1))

Andere Bezeichnung: TPP1

Hintergrund:

Synonyms: Tripeptidyl-peptidase 1,TPP-1,3.4.14.9,Cell growth-inhibiting gene 1 protein,Lysosomal pepstatin-insensitive protease,LPIC,Tripeptidyl aminopeptidase,Tripeptidyl-peptidase I,TPP-I,TPP1,CLN2,GIG1, UNQ267/PRO304,

Tissue Specificity: Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.

Background: Tripeptidyl-peptidase 1, also known as Lysosomal pepstatin-insensitive protease, is an enzyme that in humans is encoded by the TPP1 gene. This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.

Molekulargewicht: 39 kDa

Gen-ID: 1200

UniProt: O14773

Pathways: Zellzyklus, ER-Nucleus Signaling