Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

ATF2 Antikörper (AA 93-450)

ATF2 Reaktivität: Human, Maus, Ratte WB, IHC, IHC (fro), FACS Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043791
  • Target Alle ATF2 Antikörper anzeigen
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Bindungsspezifität
    • 42
    • 39
    • 26
    • 25
    • 25
    • 24
    • 24
    • 23
    • 15
    • 14
    • 14
    • 13
    • 13
    • 11
    • 9
    • 8
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 93-450
    Reaktivität
    • 303
    • 234
    • 200
    • 17
    • 12
    • 11
    • 8
    • 7
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 331
    • 15
    • 2
    • 1
    Kaninchen
    Klonalität
    • 319
    • 30
    Polyklonal
    Konjugat
    • 163
    • 18
    • 11
    • 11
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 9
    • 7
    • 7
    • 7
    • 7
    • 7
    • 7
    • 3
    • 2
    Dieser ATF2 Antikörper ist unkonjugiert
    Applikation
    • 252
    • 125
    • 119
    • 118
    • 86
    • 64
    • 58
    • 42
    • 29
    • 18
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Flow Cytometry (FACS)
    Verwendungszweck
    Anti-ATF2 Antibody Picoband®
    Kreuzreaktivität (Details)
    No cross-reactivity with other proteins
    Produktmerkmale
    Anti-ATF2 Antibody Picoband® (ABIN3043791). Tested in Flow Cytometry, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human ATF2 recombinant protein (Position: E93-E450). Human ATF2 shares 99% amino acid (aa) sequence identity with both mouse and rat ATF2.
    Isotyp
    IgG
    Top Product
    Discover our top product ATF2 Primärantikörper
  • Applikationshinweise
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
    Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat
    Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human1. "Entrez Gene: ATF2 activating transcription factor 2" 2. Bhoumik A, Takahashi S, Breitweiser W, Shiloh Y, Jones N, Ronai Z (May 2005). "ATM-dependent phosphorylation of ATF2 is required for the DNA damage response". Mol. Cell 18 (5): 577-87.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Target
    ATF2 (Activating Transcription Factor 2 (ATF2))
    Andere Bezeichnung
    ATF2 (ATF2 Produkte)
    Hintergrund

    Synonyms: Cyclic AMP-dependent transcription factor ATF-2,cAMP-dependent transcription factor ATF-2,2.3.1.48 ,Activating transcription factor 2,Cyclic AMP-responsive element-binding protein 2,CREB-2,cAMP-responsive element-binding protein 2,HB16,Histone acetyltransferase ATF2,cAMP response element-binding protein CRE-BP1,ATF2,CREB2, CREBP1,

    Tissue Specificity: Ubiquitously expressed, with more abundant expression in the brain.

    Background: ATF2, also known as Activating transcription factor 2, is a protein that in humans is encoded by the ATF2 gene. It is mapped to 2q31.1. This gene encodes a transcription factor that is a member of the leucine zipper family of DNA-binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus, it may represent a class of sequence-specific factors that activate transcription by effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.

    Sequence Similarities: Belongs to the bZIP family. ATF subfamily.

    Molekulargewicht
    65-70 kDa
    Gen-ID
    1386
    UniProt
    P15336
    Pathways
    MAPK Signalweg, RTK Signalweg, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
Sie sind hier:
Chat with us!