CARD9 Antikörper (AA 521-536)

Produktnummer ABIN303199

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CARD9 in WB, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CARD9 Antikörper (AA 521-536) (ABIN303199)

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARD9 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-CARD9 Antikörper

Bindungsspezifität: AA 521-536

Sequenz: DRENTTGSDN TDTEGS

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Immunoaffinity Chromatography.

Immunogen: Synthetic peptide - KLH conjugated corresponding to Amino Acids 521-536 of Human CARD9. The sequence is different from that of Rat origin by two Amino Acids.

Anwendungsinformationen

Applikationshinweise: Western Blot (0.5-1 μg/mL). Immunocytochemistry. Immunohistochemistry on Paraffin Sections (10 μg/mL). This antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody LS-D1, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.

Details zu CARD9

Target: CARD9 (Caspase Recruitment Domain Family, Member 9 (CARD9))

Andere Bezeichnung: CARD9

Hintergrund: Apoptosis is related to many diseases and development. Cell death signals are transduced by death domain (DD), death effector domain (DED), and caspase recruitment domain (CARD) containing molecules. CARD containing proteins include some caspases, Apaf-1, CARD4, IAPs, RICK, ARC, RAIDD, BCL-10, and ASC. A novel CARD-containing protein was recently identified and designated CARD9, which interacts with the CARD activation domain of BCL-10. CARD9 associates with BCL-10 and forms a complex within cells. CARD9 induces apoptosis and activates NF-kB. CARD9 is an upstream activator of BCL-10 and NF-kB signaling.Synonyms: Caspase recruitment domain-containing protein 9

Gen-ID: 64170

NCBI Accession: NP_434700

UniProt: Q9H257

Pathways: Activation of Innate immune Response