Cyclin D3 Antikörper (AA 136-292)

Produktnummer ABIN3030597

Dieses Anti-Cyclin D3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Cyclin D3 in WB und FACS. Geeignet für Human und Ratte.

Kurzübersicht für Cyclin D3 Antikörper (AA 136-292) (ABIN3030597)

Target: Cyclin D3 (CCND3)

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin D3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Cyclin D3 Antikörper

Bindungsspezifität: AA 136-292

Aufreinigung: Antigen affinity

Immunogen: Human partial recombinant protein (AA 136-292) was used as the immunogen for this Cyclin D3 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting amounts. Titration of the Cyclin D3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,FACS: 1-3 μg/10^6 cells

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: -20 °C

Informationen zur Lagerung: After reconstitution, the Cyclin D3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Details zu Cyclin D3

Target: Cyclin D3 (CCND3)

Andere Bezeichnung: Cyclin D3

Hintergrund: Cyclin D3 is a protein that in humans is encoded by the CCND3 gene. It is mapped to 6p21.1. The protein encoded by this gene belongs to a family of proteins whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin D3 forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. In addition, overexpression of CCND3 upregulated the translational activity in HeLa cells in a dose-dependent manner.

Gen-ID: 896

Pathways: Zellzyklus, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process